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Upstream Bioreactor Technology Benchtop to Manufacturing

April 8, 2021

With the growing healthcare demands, especially seen in this pandemic, there are currently more vaccine and biotherapeutic manufacturers than before to step up to the crucial requirement of speed, scale and supplies. With variety of bioreactors available in the market for development and manufacture of therapeutics, the major bottleneck to commercialization is the viability of a cell culture process in addressing scale-up and technology transfer.

Process developed on a bench scale bioreactor may meet the productivity and quality criteria, but this may not easily translate into a manufacturing process. This makes it critical to select a predictable, reproducible, robust development and manufacturing scale bioreactor platform. Additionally, a successful scale-up and technology transfer means a good understanding of the engineering aspects of the bioreactors to meet the demand of non-linear scale up parameters.

This webinar outlines the aspects of bioreactor design, characterization and scale-up of a single use stirred tank bioreactor and highlight the benefits that an advanced, flexible control system can bring to bench scale bioreactors; catering to both adherent and suspension cell culture processes.

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April 8, 2021
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